You might consider monitoring your disk usage, because this might reveal trends
that help you to plan for the future. Here, we'll use a cron job to
periodically scan a directory with the duc program by Ico Doornekamp.
I wrote a Bash script to call bigWigToBedGraph for each region in a BED
file. You can quickly take a subset of bigWig data for regions of interest.
In my particular case, I needed to get phastCons conservation scores for
putative transcription factor binding sites.